Subcutaneous injection of inhaled anesthetics produces cutaneous analgesia

Inhaled anesthetics: an historical overview.

Inhalational agents have played a pivotal role in anesthesia history. The first publicly demonstrated anesthetic of the modern era, diethyl ether, was an inhalational anesthetic. The attributes of a good agent, ability to rapidly induce anesthesia, with limited side effects has led research efforts for over a hundred and fifty years. The explosion hazard was largely conquered with the developme...

Analgesia for pain during subcutaneous injection: effectiveness of manual pressure application before injection

BACKGROUND It is necessary to establish an effective subcutaneous injection procedure for adult and elderly individuals because many drugs such as hormones and interferon are generally delivered by subcutaneous injection. We tested whether pain during subcutaneous injection can be decreased by prior application of localized manual pressure at the injection site. METHODS In this semirandomized...

Analgesia and anesthesia during IUD insertion: local anesthetics

Background: Intrauterine Device (IUD) is an effective and long term method of contraception that can be used without continued effort by the user to prevent pregnancy perfectly. Pain during IUD insertion is one of the obstacles to properly using the device. Thus, using different methods of analgesia and anesthesia to alleviate this pain has been studied by many researchers. This review article ...

Cutaneous limb inflammation produces analgesia to pressure pain in the ipsilateral forehead of healthy volunteers.

UNLABELLED To investigate the pain-modulatory effects of a local inflammatory stimulus on pain elsewhere in the body, capsaicin was applied topically to the forearm of 14 healthy female volunteers. Pressure-pain thresholds and sensitivity to sharpness were assessed on each side of the forehead twice per day during 48 hours of capsaicin treatment, and in the treated and contralateral forearm bef...

Methadone produces prolonged postoperative analgesia.